AFRJMS African Research Journal of Medical Sciences 3006-7421 Bioscience Press afrjms-1-2-002 10.62587/AFRJMS.1.2.2024.14-19 Research Paper Novel perspectives on Amentoflavone’s influence on cell cycle and apoptosis: exploring theoretical modulation of serine/threonine-kinases FerrariIvan Vito 1 * 1Institute of Clinical Physiology, National Research Council, Via Aurelia Sud, 54100 Massa, Italy. E-mail: ivanvitoferrari@gmail.com *Corresponding author: Ivan Vito Ferrari, Institute of Clinical Physiology, National Research Council, Via Aurelia Sud, 54100 Massa, Italy. E-mail: ivanvitoferrari@gmail.com 07 2024 1 2 14 19 Abstract

Docking results suggest that Amentoflavone has a higher affinity for investigated serine/threonine-protein kinases, indicating potential interactions that may influence the activities of these kinases. The negative values of the binding energies signify strong and stable interactions, suggesting that Amentoflavone could be a key molecule in modulating the functions of these kinases, which play crucial roles in cellular processes such as cell cycle regulation and apoptosis.

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